Publications

2020

Scientific considerations for global drug development

Jennifer L Wilson, Kit Wun Kathy Cheung, Lawrence Lin, Elizabeth AE Green, Analia I Porrás, Ling Zou, David Mukanga, Paul A Akpa, Delese Mimi Darko, Rae Yuan, Sheng Ding, Wiltshire CN Johnson, Howard A Lee, Emer Cooke, Carl C Peck, Steven E Kern, Dan Hartman, Yoshikazu Hayashi, Peter W Marks, Russ B Altman, Murray M Lumpkin, Kathleen M Giacomini, Terrence F Blaschke
Science Translational Medicine 12 (554)

 

An in vitro quantitative systems pharmacology approach for deconvolving mechanisms of drug-induced, multilineage cytopenias

JL Wilson, D Lu, N Corr, A Fullerton, J Lu
PLOS Computational Biology 16 (7), e1007620

 

2019

PathFXweb: a web application for identifying drug safety and efficacy phenotypes

JL Wilson, M Wong, A Chalke, N Stepanov, D Petkovic, RB Altman
Bioinformatics 35 (21), 4504-4506

 

An Overview of Genomic Biomarker Use in Cardiovascular Disease Clinical Trials

Oluseyi Adeniyi, Anuradha Ramamoorthy, Robert Schuck, Jielin Sun, Jennifer Wilson, Issam Zineh, Michael Pacanowski
Clinical Pharmacology & Therapeutics 106 (4), 841-846

 

Evaluating Angiogenic Potential of Small Molecules Using Genetic Network Approaches

Anusuya Das, Parker Merrill, Jennifer Wilson, Thomas Turner, Mikell Paige, Scott Capitosti, Milton Brown, Brandon Freshcorn, Mary Caitlin P Sok, Hannah Song, Edward A Botchwey

 

2018

PathFX provides mechanistic insights into drug efficacy and safety for regulatory review and therapeutic development

Jennifer L Wilson, Rebecca Racz, Tianyun Liu, Oluseyi Adeniyi, Jielin Sun, Anuradha Ramamoorthy, Michael Pacanowski, Russ Altman
PLoS computational biology 14 (12), e1006614

 

A scientist engineer’s contribution to therapeutic discovery and development

JL Wilson
Experimental Biology and Medicine 243 (14), 1125-1132

 

Biomarkers: Delivering on the expectation of molecularly driven, quantitative health

JL Wilson, RB Altman
Experimental Biology and Medicine 243 (3), 313-322

 

Functional Genomics Approach Identifies Novel Signaling Regulators of TGFα Ectodomain Shedding

Jennifer L Wilson, Eirini Kefaloyianni, Lauren Stopfer, Christina Harrison, Venkata S Sabbisetti, Ernest Fraenkel, Douglas A Lauffenburger, Andreas Herrlich
Molecular Cancer Research 16 (1), 147-161

 

2016

Pathway-based network modeling finds hidden genes in shRNA screen for regulators of acute lymphoblastic leukemia

JL Wilson, S Dalin, S Gosline, M Hemann, E Fraenkel, DA Lauffenburger
Integrative Biology 8 (7), 761-774

 

2013 and earlier

Integrated network analyses for functional genomic studies in cancer

JL Wilson, MT Hemann, E Fraenkel, DA Lauffenburger
Seminars in cancer biology 23 (4), 213-218

 

Harnessing systems biology approaches to engineer functional microvascular networks
LS Sefcik, JL Wilson, JA Papin, EA Botchwey
Tissue Engineering Part B: Reviews 16 (3), 361-370
 
 

The influence of prior industry experience and multidisciplinary teamwork on student design learning in a capstone design course

K Gruenther, R Bailey, J Wilson, C Plucker, H Hashmi
Design Studies 30 (6), 721-736