Thesis defense: Dr. Josh Kenchel

Congratulations to Dr. Josh Kenchel for a successful hybrid thesis defense on June 3, 2022! In a riveting presentation, Josh described nearly five years of work on ribozyme evolution, bringing new evolutionary concepts as well as analytical chemistry techniques to his...
Thesis defense: Dr. Yuning Shen

Thesis defense: Dr. Yuning Shen

Congratulations to Dr. Yuning Shen for successfully defending his thesis on February 24, 2022! In his work, Yuning merged our experimental methods with statistical and computational tools he learned, including from co-advisor Professor Ambuj Singh, Dept. of Computer...

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Thesis defense: Dr. Baoqing Zhou

Thesis defense: Dr. Baoqing Zhou

Congratulations to Dr. Baoqing Zhou for a successful pandemic-style thesis defense! Setting up and analyzing a new microbial ecosystem in the lab made for a challenging but rewarding project. We wish her the best of luck on her future endeavors as she wraps up the...

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Thesis defense: Dr. Ray Borg

Thesis defense: Dr. Ray Borg

Congratulations to Dr. Ray Borg for successfully defending his thesis on September 16, 2021! Ray described a collaboration with Prof. Arnab Mukherjee's laboratory at UCSB, to develop phages for biomedical imaging. The defense was virtual but the spirit was real. Best...

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Thesis defense: Dr. Janzen

Thesis defense: Dr. Janzen

Congratulations to Dr. Evan Janzen for a well-deserved finish to his graduate studies! Five years of dedicated work spanning organic synthesis, RNA biochemistry, and bioinformatics was summarized in an excellent thesis defense. Dr. Janzen will be venturing across the...

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Why do phages tolerate molecular engineering?

Why do phages tolerate molecular engineering?

When Huan Peng first cloned M13 chimeras by mix-and-match with other filamentous phages, in order to change the host targeted, we thought we'd probably need to do at least a little directed evolution to improve the folding or affinity of the new chimeras. That was not...

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Thesis defense: Dr. Tran

Thesis defense: Dr. Tran

Congratulations to Dr. Claire Tran on successfully defending her thesis! We will miss her hard-won expertise in protein and RNA biochemistry as well as her carefully crafted 'joke' slides. Dr. Tran is heading to Boston to join i2o Therapeutics.

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Processing Illumina data from in vitro evolution

Processing Illumina data from in vitro evolution

A few years ago, Celia Blanco and Sam Verbanic began analyzing Illumina data from our collaborator Burckhard Seelig's laboratory. Since our existing tools were written for ribozyme selections, Celia and Sam wrote some new scripts to pre-process the data. Others in the...

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