The microbiome of chronic wounds

The microbiome of chronic wounds

We first started to wonder about the impact that phages might have on polymicrobial, long-term bacterial communities, such as those that colonize chronic wounds, a few years ago. Studying this question requires characterization of both the bacterial and the phage...
Rapid bacterial detection and antibiotic susceptibility

Rapid bacterial detection and antibiotic susceptibility

To identify bacterial pathogens and determine the best antibiotics to use, clinical laboratories use ‘culture and sensitivity’, or growth of bacteria on selective media. This process takes days to yield results, which is a long time during a bacterial...
Controlled phage therapy

Controlled phage therapy

Phages have been considered for antibacterial therapy ever since they were discovered in the early 20th century. However, significant concerns about their self-replicating, evolving nature have been difficult to avoid. For example,  phages can spread antibiotic...